الكشف عن الأثر المتبقي للديكلازرويل في لحم و كبد الفروج في محافظة طرطوس باستخدام الكروماتوغرافيا السائلة عالية الأداء

Abstract

Diclazuril is a triazinone-class coccidiostat used to control Eimeria spp. parasites responsible for coccidiosis in broiler chickens. In this research, 80 samples (40 meat samples and 40 liver samples) were collected from 40 Broiler carcasses in four different regions of Tartous Governorate (Dreikish، Sheikh Badr، Safita، Baniyas)،)10 carcasses sampled from each region. The study aimed to detect diclazuril residues in Broiler meat and liver using high-performance liquid chromatography (HPLC). The results showed that 24 samples were negative for diclazuril residues (30%)، while 56 samples tested positive (70%). Among the positive samples، 20 were from the Al-Dreikish region، 16 from Sheikh Badr، 12 from Safita، and 8 from Baniyas. The highest mean of diclazuril concentrations was found in Broiler meat and liver samples from Al-Dreikish (190.061 μg/kg and 956.426 μg/kg wet weight، respectively)، while the lowest mean concentrations were detected in samples from Baniyas (24.527 μg/kg in meat and 217.43 μg/kg in liver).

 All diclazuril concentrations in liver samples were within the permissible limits. However، among the 40 meat samples analyzed، only one exceeded the maximum permissible level (MRL) (2.5% of total meat samples، or 3.57% of the 28 positive samples). This is according to the Codex Alimentarius Commission (CAC)، which has set the maximum permissible level for diclazroyl in chicken muscles at 500 μg/kg، and in liver at 3000 μg/kg.