Study of the effectiveness of Cyclamen persicum extracts against some pathogenic bacteria isolated from upper respiratory infections

Abstract

Upper respiratory tract infections are among the most common infectious diseases, and bacterial causes can lead to severe forms of the disease due to their acute complications. This research investigated the production of an alcoholic extract of saponins found in the tubers of Cyclamen persicum, a plant prevalent in the Levant. The inhibitory activity of this extract was tested on 60 bacterial isolates of Gram-positive Staphylococcus aureus and Gram-negative Pseudomonas aeruginosa from patients at latakia university hospital The study demonstrated the inhibitory effect of the plant extract on bacterial growth and its synergistic effect with a group of antibiotics commonly used to treat the disease